Christine M. O’Keefe, Ph.D.

BioMedical Engineer & Social Media Manager

Dr. O’Keefe is postdoctoral researcher at Johns Hopkins University. She has a B.S. in Bioengineering from University of Maryland, College Park and a Ph.D. in Biomedical Engineering from Johns Hopkins University.  During her undergraduate studies, she designed an RF-based tracking device to monitor endotracheal tube positioning and prevent distal migration into the lungs during intubation. She also developed an ode -based computational model of neuronal outgrowth in response to calcium gated ion channel activity. While pursuing her graduate degree,  Dr. O’Keefe developed a microfluidic platform to detect and quantify epigenetic heterogeneity with respect to DNA methylation, particularly for rare species identification in liquid biopsies. She has gained extensive experience in microfabrication, assay optimization, thermal stabilization, image processing, and data processing and analysis methods. Dr. O’Keefe is part of a cancer research team using the microfluidic digital platform to investigate the utility of epigenetic heterogeneity in diagnostics, theranostics, and mechanistic studies.